A very interesting comment in Joel Spolksy’s discussion forum:

If I started up my very own major software project now, I would make my language decision based on the criteria above. Sure, I love Lisp, CLOS is awesome, real lexical scoping rocks, Lisp macros are way cool (when used as directed), and personally I really like Lisp syntax. […] But it would take a lot, or require special circumstances, to persuade me to choose Lisp for a major software project, if I were in charge of making the choice.

It’s interesting not only because of its content, but because it has been written by Dan Weinreb, whose LISP competency can’t really be in doubt ;-)